Preparation method of Balofloxacin intermediate

The invention relates to a preparation method of a Balofloxacin intermediate. The invention relates to the field of compound synthesis and in particular relates to a method for preparing 3-methylaminopiperidine by 3-pyridinemethaneamine. According to the method, the 3-pyridinemethaneamine is derived...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG JIANLIANG, GUO ZHENRONG, CHEN ZHE, ZHU HANGCHANG, ZHANG KEHUA, FENG LICHUN, YAO CHEN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Beschreibung
Zusammenfassung:	The invention relates to a preparation method of a Balofloxacin intermediate. The invention relates to the field of compound synthesis and in particular relates to a method for preparing 3-methylaminopiperidine by 3-pyridinemethaneamine. According to the method, the 3-pyridinemethaneamine is derived, and then pyridine ring is deoxidated by palladium on carbon to obtain the 3-methylaminopiperidine. Compared with the conventional method for directly deoxidating the 3-pyridinemethaneamine, the method uses the palladium on carbon for replacing platinum dioxide for serving as a catalyst so that the cost is greatly reduced so as to be beneficial to mass production.