Biological adhesion colon positioning micro-chip for treating ulcerative colitis

The invention relates to a biological adhesion colon positioning micro-chip for treating ulcerative colitis. The problem that the compliance of a patient is poor because drug metabolism is inactivated by a first-pass effect can be effectively solved. The technical scheme is that the micro-chip is pr...

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Bibliographische Detailangaben
Hauptverfasser: PING JIAYI, LI XUELIN, DUAN XIAOYING, ZHANG HUI, CHEN TIANCHAO, WANG WEIHONG, WANG XIAOXIAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a biological adhesion colon positioning micro-chip for treating ulcerative colitis. The problem that the compliance of a patient is poor because drug metabolism is inactivated by a first-pass effect can be effectively solved. The technical scheme is that the micro-chip is prepared from the following components in weight: 14 to 17g of sophorae flavescentis, 9 to 11g of dark plum, 11 to 13g of tree-of-heaven ailanthus bark, 2.35 to 2.75g of fructus evodiae, 3 to 4g of Carbomer 934P, 9 to 11g of hydroxy propyl cellulose, 0.7 to 0.84g of beta-cyclodextrin, 1.44 to 1.64g of polyacrylic resin S100, 0.35 to 0.4g of diethyl phthalate and 0.11 to 0.13g of magnesium stearate. The biological adhesion colon positioning micro-chip is simple in preparation process, short in time consumption, standard in quality, easy to control and good in using effect and is an innovation for medicaments for treating ulcerative colitis.