Application of altenusin compound and pharmaceutically acceptable salt thereof in preparation of medicaments for treating FXR-mediated diseases

The invention provides an application of a chemical compound, particularly relates to an medicinal application of altenusin compound with structural formulas (1) and pharmaceutically acceptable salt thereof and more particularly relates to an application of altenusin compound and pharmaceutically ac...

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Hauptverfasser: MU DONG, ZHENG HAIZHOU, ZHENG ZHIHUI, SHEN WENBIN, CAI CHAOJING, SHAN YUEQI, DUAN BAOLING, REN XIAO, HUO PEIYUAN, ZHAO FENG, XU YAN, KE AIBING, FAN YULING, LIN JIE, MU YUNLONG, LI YEYING, SHI YING, LU XINHUA, DING YANBO, LI RUOLAN, CUI XIAOLAN, ZHU JINGTONG, ZHANG XUELIAN, CAO LIN, MA YING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides an application of a chemical compound, particularly relates to an medicinal application of altenusin compound with structural formulas (1) and pharmaceutically acceptable salt thereof and more particularly relates to an application of altenusin compound and pharmaceutically acceptable salt thereof in preparation of medicaments for preventing and treating related FXR-mediated diseases and particularly medicaments for treating obesity, diabetes, metabolic syndrome, cholestatic liver diseases, organ fibrosis, non-alcoholic cirrhosis, cholesterol gallstones, inflammation and other diseases, and therefore, more selections are provided for clinical medicaments.