Synthesis method of 1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formate

The invention discloses a synthesis method of 1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formate. According to the synthesis method, the 1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formate is prepared by condensation of 2,4-dioxobutanoate and 2-hydrazyl-3-chloropyridine, and the 2,4-dioxobutanoate is prepared by Claisen condensation of pyruvate and formate. The synthesis method disclosed by the invention has the characteristics of cheap and available raw materials, short technological process, simple operation steps, mild reaction condition, low energy consumption and low cost; besides, the synthesis method avoids poisonous raw materials adopted by a traditional method, reduces the corrosion to equipment and the danger to the health of operators; moreover, the synthesis method has little discharge of the three wastes and is beneficial to realizing the industrial application; therefore, the synthesis method disclosed by the invention is an environmentally friendly, economical and effective synthesis route.