Application of 5-hydroxymethyl-2-furfural and derivatives thereof in preparation of pharmaceutical compositions for preventing and treating bone metabolic disorder diseases

The invention provides application of a compound of formula (I) and medicinal salts thereof in preparation of pharmaceutical compositions for preventing and treating bone metabolic disorder diseases. In the formula (I), R1 represents hydroxyl or C1-C6 alkyl ester groups; X represents O, NR2, NOH or...

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Bibliographische Detailangaben
Hauptverfasser: PAN DANMIN, QIAN XIAOWEI, ZHANG YANHONG, QIANG LIMIN, TAN XIANGLING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides application of a compound of formula (I) and medicinal salts thereof in preparation of pharmaceutical compositions for preventing and treating bone metabolic disorder diseases. In the formula (I), R1 represents hydroxyl or C1-C6 alkyl ester groups; X represents O, NR2, NOH or NOOR3, wherein R2 represents H or C1-6 alkyls, and R3 represents C1-6 alkyls. The invention also provides a compound of a formula (II) and medicinal salts thereof in preparation of pharmaceutical compositions for preventing and treating bone metabolic disorder diseases. In the formula (II), R1 represents hydroxyl or C1-C6 alkyl ester groups; and n=1 or 2.