Reconfigurable leak testing system

A reconfigurable leak testing system includes a leak testing station, an off-shuttle disposed adjacent to the leak testing station, and a fixture cartridge that is translatable between the off-shuttle and the leak testing station. The fixture cartridge is configured to selectively couple with the leak testing station and includes an upper fixture, a lower fixture, and a plurality of actuatable testing features. The fixture cartridge is configured to receive a part between the upper fixture and lower fixture, and the plurality of actuatable testing features are configured to contact the received part to create a closed volume adjacent the part, wherein the closed volume may be pressurized via a pressurized fluid, and examined for leaks.