Bio-adhesive temperature-sensitive in-situ gel for treating reflux esophagitis

The invention relates to a bio-adhesive temperature-sensitive in-situ gel for treating reflux esophagitis, which can effectively solve the problems of relapse after withdrawal and low curative effect in the prior art. According to the technical scheme, the gel is prepared by the following steps of:...

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Bibliographische Detailangaben
Hauptverfasser: GUO SHUYUN, LI XUELIN, DUAN XIAOYING, WU CAILI, CHEN TIANCHAO, WANG XIAOXIAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a bio-adhesive temperature-sensitive in-situ gel for treating reflux esophagitis, which can effectively solve the problems of relapse after withdrawal and low curative effect in the prior art. According to the technical scheme, the gel is prepared by the following steps of: preparing 1,000 millimeters of weeping forsythiae, dandelion, pseudo-ginseng, poloxamer 407, poloxamer 188, hydroxypropyl methyl cellulose and water, crushing the pseudo-ginseng into coarse powder, refluxing and extracting with ethanol for three times, combining the extracts, reclaiming the ethanol, concentrating into thick pseudo-ginseng paste, decocting the pseudo-ginseng residue, the weeping forsythiae and the dandelion for three times by adding the water, combining the decoction, filtering to obtain a first medicinal liquid, concentrating the first medicinal liquid, then adding ethanol, centrifuging, taking supernate, reclaiming the ethanol till the ethanol smell does not exist, combining the supernate and the