Method for identifying key proteins based on characteristics of structural domain
The invention discloses a method for identifying key proteins based on characteristics of a structural domain. For all proteins of species, the method comprises the following steps of: obtaining structural domain information through using a database or carrying out analysis of protein sequences, cou...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a method for identifying key proteins based on characteristics of a structural domain. For all proteins of species, the method comprises the following steps of: obtaining structural domain information through using a database or carrying out analysis of protein sequences, counting the frequency of occurrence of each structural domain type in the proteins on the basis of the structural domain information, and calculating the weight of each protein according to the statistical result, wherein the bigger is the weight, the more possibility of the protein is to form the key protein. The method is simple and effective, is only based on the structural domain information of the protein and does not rely on the network information of protein interactions and the like, so that the huge amount of manpower and material resources consumed in biological experiments can be avoided. Compared with a random method, the method provided by the invention can be used for accurately identifying key proteins |
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