Preparation method of propyl o-fluorobenzene compound
The invention relates to a preparation method of propyl o-fluorobenzene compounds. The preparation method comprises the following steps that lithium reagent is firstly prepared by using a raw material compound I, then coupling reaction occurs between the lithium reagent and allyl chloride or allyl b...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a preparation method of propyl o-fluorobenzene compounds. The preparation method comprises the following steps that lithium reagent is firstly prepared by using a raw material compound I, then coupling reaction occurs between the lithium reagent and allyl chloride or allyl bromide under the catalytic effect of copper, and the obtained product is catalytically hydrogenated to obtain the propyl o-fluorobenzene compounds. The preparation method of propyl o-fluorobenzene compounds provided by the invention has the advantages that the steps are fewer, the yield is high, the method is environmental-friendly, the industrialization is easy to realize, and the problems of more steps, great pollution, fluorine falling and the like in the prior art are solved. |
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