Tanshinone IIA lipid microsphere preparation and preparation method thereof

The invention relates to a tanshinone IIA lipid microsphere preparation and a preparation method thereof. 1000 ml of the preparation is prepared according to a formula, wherein the formula comprises, by weight, 0.01-1.0 g of tanshinone IIA, 10-200.0 g of oil for injection, 2.0-20 g of an emulsifying agent, 4.0-10.0 g of an isotonic regulator and the balance of water. According to the preparation method, a drug and phospholipid are firstly dissolved in a suitable solvent, then the solvent is removed, and the resulting material is added to an oil phase, wherein entrapment rate of the prepared product is significantly improved, a disadvantages of poor water solubility of the tanshinone IIA is overcome with the preparation method, a lipid microsphere preparation with characteristics of low toxic reaction, low irritation, long effect time, sustaining and targeting is provided, a process is simple process, cost is low, and the method is applicable for industrial production.