3-(3-quinolyl)-2-propenyl-1-halide and its preparation method
The invention relates to the technical field of a novel intermediate compound of cethromycin and a preparation method thereof. The intermediate is 3-(3-quinolyl)-2-propenyl-1-halide as shown in the formula defined in the specification, wherein X represents bromine, chlorine or iodine. The invention...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to the technical field of a novel intermediate compound of cethromycin and a preparation method thereof. The intermediate is 3-(3-quinolyl)-2-propenyl-1-halide as shown in the formula defined in the specification, wherein X represents bromine, chlorine or iodine. The invention provides a novel intermediate compound 3-(3-quinolyl)-2-propenyl-1-halide, which can react with erythromycin A 9-Oxime to conveniently obtain an erythromycin derivative compound as shown in the formula (V). In the meanwhile, the preparation method of the novel halide is simple, and the halide can be obtained by one-step reaction of present compounds. |
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