A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma

A monoclonal anti-CD44 antibody,or antigen-binding fragment thereof,for use in the treatment of a head and neck squamous cell carcinoma (HNSCC) in a mammal, wherein said HNSCC is characterized by the expression of CD44. Said monoclonal antibody may be produced by the hybridoma deposited with the ATC...

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Bibliographische Detailangaben
Hauptverfasser: FRANZMANN ELIZABETH JANE, DA CRUZ LUIS A. G
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A monoclonal anti-CD44 antibody,or antigen-binding fragment thereof,for use in the treatment of a head and neck squamous cell carcinoma (HNSCC) in a mammal, wherein said HNSCC is characterized by the expression of CD44. Said monoclonal antibody may be produced by the hybridoma deposited with the ATCC with the accession number PTA-4621,and may be chimeric or humanized versions thereof.