Method for removing/inactivating prion in glycoprotein
The invention discloses a method for removing/inactivating prion in glycoprotein. The method comprises one or a plurality of steps as follows: (a) filtering glycoprotein-containing solution with a microporous membrane; (b) filtering the glycoprotein-containing solution with a nano-filtration membran...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a method for removing/inactivating prion in glycoprotein. The method comprises one or a plurality of steps as follows: (a) filtering glycoprotein-containing solution with a microporous membrane; (b) filtering the glycoprotein-containing solution with a nano-filtration membrane or an ultrafiltration membrane; and (c) carrying out anion exchange chromatography to the glycoprotein-containing solution, wherein the order of the steps can be randomly exchanged. |
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