Pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and antitumor effect thereof

The invention relates to the field of medicinal chemistry, in particular to a pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and the antitumor effect thereof. Pharmacological experiment results show that the compound provided by the invention has remarkable antiproliferative activity to vario...

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Hauptverfasser: WU XIHAN, YANG MINMIN, SHU QINGNING, YU YANG, ZHU CHUNRUI
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creator WU XIHAN
YANG MINMIN
SHU QINGNING
YU YANG
ZHU CHUNRUI
description The invention relates to the field of medicinal chemistry, in particular to a pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and the antitumor effect thereof. Pharmacological experiment results show that the compound provided by the invention has remarkable antiproliferative activity to various human tumor cell strains, and can be used for curing cancers, especially solid tumors such as stomach cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostate cancer and oral cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and antitumor effect thereof
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