Pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and antitumor effect thereof

The invention relates to the field of medicinal chemistry, in particular to a pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and the antitumor effect thereof. Pharmacological experiment results show that the compound provided by the invention has remarkable antiproliferative activity to vario...

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Hauptverfasser:	WU XIHAN, YANG MINMIN, SHU QINGNING, YU YANG, ZHU CHUNRUI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to the field of medicinal chemistry, in particular to a pyrrole-(2, 1-f) (1, 2 and 4) triazine derivative (I) and the antitumor effect thereof. Pharmacological experiment results show that the compound provided by the invention has remarkable antiproliferative activity to various human tumor cell strains, and can be used for curing cancers, especially solid tumors such as stomach cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostate cancer and oral cancer.