Ambroxol hydrochloride glucose injection and preparation method thereof

The invention discloses ambroxol hydrochloride glucose injection and a preparation method thereof, which is composed of ambroxol hydrochloride, glucose, activated carbon and injection water. The preparation method comprises taking 50% of the injection water to be boiled, adding the glucose to be dis...

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Bibliographische Detailangaben
Hauptverfasser: LONG WEN, SHEN XIN, ZHU YONG, RAN LIANGJI, WANG LICHUN, LIANG LONG, CHEN LI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses ambroxol hydrochloride glucose injection and a preparation method thereof, which is composed of ambroxol hydrochloride, glucose, activated carbon and injection water. The preparation method comprises taking 50% of the injection water to be boiled, adding the glucose to be dissolved, adding the activated carbon to adsorb, decarburizing, placing filter liquid in a dilution tank, filling nitrogen after the filter liquid is arranged in the dilution tank, then adding ambroxol hydrochloride to be dissolved, adding the remaining injection water, cooling to 40 DEG C to 50 DEG C with circulation cooling water, measuring a potential of hydrogen (pH) value and content of the ambroxol hydrochloride, filtering with a 0.22-mum micropore filter film until liquid medicine is clear, filling and packing the liquid medicine, respectively filling nitrogen in an empty bottle before filling and packing and a bottle after filling and packing, arranging a cement plug, firming a cover,sterilizing and obtaining