Substrate for selecting and specifically influencing the function of cells

The invention relates to a method and to a substrate for selecting and specifically influencing the function of cells by the adhesion thereof to substrate surfaces having prescribed properties. Said substrates comprise various surface regions each representing a condition affecting the cell adhesion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SCHMIEDER ANN-KATHRIN, SPATZ JOACHIM P, PERSCHMANN NADINE, FIAMMENGO ROBERTO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a method and to a substrate for selecting and specifically influencing the function of cells by the adhesion thereof to substrate surfaces having prescribed properties. Said substrates comprise various surface regions each representing a condition affecting the cell adhesion and/or cell function, and said conditions are determined by a geometric property and/or a mechanical property or a combination of a geometric property and/or a mechanical property with a chemical property of each surface region. The invention further relates to analysis devices and to analysis methods using said substrates for identifying and selecting particular cell types, for identifying suitable substrate conditions for affecting a particular cell function or particular cell type or for identifying disease states characterized by a change in the cell type or cell function.