Pyridine-3-carboxyamide derivative

Pyridine-3-carboxyamide derivative

To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjögren syndrome, Behcet's disease, type I diabetes mell...

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Hauptverfasser: ASHIKAWA MASANORI, OZAWA TAKATOSHI, KOUKETSU AKIYASU, ISHIKAWA TETSUYA, TAKEMURA SHUNJI, TABUNOKI YUICHIRO, SHIBASAKI MANABU, ISHIWATA HIROYUKI, SHIGEMI RYOTA, MIYAKE YOSHIHARU, SATO SEIICHI, YAMADA HAJIME, DOI TAKESHI, KITAMURA TAKAHIRO, TAMURA MASAHIRO
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjögren syndrome, Behcet's disease, type I diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof.