CA-4 derivatives and preparation method and medicinal application thereof

The invention relates to the field of pharmaceutical chemistry, in particular to CA-4 derivatives (I) and a preparation method thereof, and the inhibitory effect of the CA-4 derivatives on tumor blood vessels. Pharmacological experiments prove that the compounds can be used for treating angiogenesis...

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Bibliographische Detailangaben
Hauptverfasser: TU ZHEWEI, WU MENGXI, SI CHONGJING, DAI YUCHI, HE GUANGWEI, SUN LI, HE SHUYING, BIAN JINLEI, XU YUNGEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the field of pharmaceutical chemistry, in particular to CA-4 derivatives (I) and a preparation method thereof, and the inhibitory effect of the CA-4 derivatives on tumor blood vessels. Pharmacological experiments prove that the compounds can be used for treating angiogenesis-related diseases such as various cancers and chronic inflammation, and other angiogenic diseases.