Biological detection method based on nano-palladium label and catalytic deposition amplification function thereof

The invention provides a biological detection method based on a nano-palladium label and a catalytic deposition amplification function thereof, which is a biologic molecular detection method for detecting by combining a catalytic property of nano-Pd and utilizing chemical plating for signal amplific...

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Hauptverfasser: WANG ZHIFEI, SHEN BIN, YAN SHIFEI, HE NONGYUE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a biological detection method based on a nano-palladium label and a catalytic deposition amplification function thereof, which is a biologic molecular detection method for detecting by combining a catalytic property of nano-Pd and utilizing chemical plating for signal amplification and finally by dint of optical, magnetic and other properties represented after the chemical plating. In the route, Pd particles with the particle size of about 1-100nm are firstly synthesized and then modified by means of a surface chemical technology so as to enable the Pd particles to exist in a buffer solution stably and connect biomolecules to be labeled to the surfaces of the Pd particles, and thus, the nano-Pd labeling of the biomolecules is completed; then, after biomolecular interaction is completed, detection signals are amplified through a chemical plating process by utilizing the catalytic property of Pd; and finally, a means for detection is based on optical, magnetic or other properties represen