Preparation method of biological function composite auxetic hydrogel with shell core structure

The invention belongs to the field of biomedical material and relates to a preparation method of biological function composite auxetic hydrogel with shell core structure. In the method, the biological function composite auxetic hydrogel with shell core structure is prepared by the radiation cross-linking technology or freezing/unfreezing method, i.e. an inner core is of a dense structure with lowwater content, and an outer shell is of a communicated porous structure with relatively low modulus. Macroscopically, a negative Poisson's ratio effect of the material is realized, and the inner coreand outer shell are in firm combination. By controlling the core component and size as well as the shell composition and structure of the material, the auxetic hydrogel meeting various application requirements can be prepared; by controlling the radiation dosage in the radiation cross-linking as well as the parameters of the freezing/unfreezing process such as temperature, time, circulation timesand the like, the condensed