Preparation method of 2-O-ethoxyl-D-glucose

Preparation method of 2-O-ethoxyl-D-glucose

The invention provides a preparation method of 2-O-ethoxyl-D-glucose, belonging to the technical field of chemical synthesis. The method comprises the following steps of: carrying out glucoside treatment on merchant D-glucose, and protecting 4,6-site hydroxyl groups with benzaldehyde; and then selec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHEN YAOJUAN, HOU HONGXIA, YANG YANSHOU, FU YING
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The invention provides a preparation method of 2-O-ethoxyl-D-glucose, belonging to the technical field of chemical synthesis. The method comprises the following steps of: carrying out glucoside treatment on merchant D-glucose, and protecting 4,6-site hydroxyl groups with benzaldehyde; and then selectively carrying out nucleophilic substitution and hydrolysis with 2-bromoethanol pyran ether to synthesize the 2-O-ethoxyl-D-glucose. The method has the advantages of low cost and easiness of obtaining raw materials, moderate reaction condition, fewer synthesis steps, high productivity, convenience for operation, and the like.