Method for preparing amlodipine

The invention relates to the pharmaceutical chemistry field and particularly discloses a method for preparing amlodipine. The preparation method is as follows: the compound shown in the structural formula (II) and aminoethanol are used to perform nucleophilic substitution reaction in the presence of alkali and obtain amlodipine, wherein the X in the structural formula (II) is a leaving group; and the leaving group can be any of leaving groups which are acceptable in pharmacy, such as -OSO2CH3, -OSO2Ph, -OSO2Ph or halogen Cl, Br or I. By adopting the preparation method of the invention, amlodipine can be prepared from the known raw materials in one step, thus the steps of protecting the amino group of the intermediate and releasing the amino protective group can be avoided, the drug impurities brought to the production process can be strictly controlled, the prepared amlodipine has high purity and the safety of the drug and the high efficiency can be ensured.