Clopidogrel bisulfate tablet and preparation method thereof

The invention relates to a clopidogrel bisulfate tablet and a preparation method thereof. Each clopidogrel bisulfate tablet comprises 25-75 mg of clopidogrel bisulfate measured in the term of clopidogre, fillers, disintegrants, solubilizers, flow aids and lubricants. In the invention, the method of...

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Hauptverfasser: ZHAO XIAOHONG, GAI HAITAO, WANG YONGJUN, SUN HAITANG, CHEN ZAIXIN, MAO BAIYANG, WANG ZHIGANG, XIE RUILI, GUO WEN
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creator ZHAO XIAOHONG
GAI HAITAO
WANG YONGJUN
SUN HAITANG
CHEN ZAIXIN
MAO BAIYANG
WANG ZHIGANG
XIE RUILI
GUO WEN
description The invention relates to a clopidogrel bisulfate tablet and a preparation method thereof. Each clopidogrel bisulfate tablet comprises 25-75 mg of clopidogrel bisulfate measured in the term of clopidogre, fillers, disintegrants, solubilizers, flow aids and lubricants. In the invention, the method of adding granular microcrystalline cellulose and aerosil through airflow crushing disposal to a prescription is adopted, therefore, the process of dry granulating is simple and feasible, reproducibility is good, prepared products have high stability, and the requirement of continuous large-scale production can be satisfied.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Clopidogrel bisulfate tablet and preparation method thereof
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