Clopidogrel bisulfate tablet and preparation method thereof

The invention relates to a clopidogrel bisulfate tablet and a preparation method thereof. Each clopidogrel bisulfate tablet comprises 25-75 mg of clopidogrel bisulfate measured in the term of clopidogre, fillers, disintegrants, solubilizers, flow aids and lubricants. In the invention, the method of...

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Bibliographische Detailangaben
Hauptverfasser: ZHAO XIAOHONG, GAI HAITAO, WANG YONGJUN, SUN HAITANG, CHEN ZAIXIN, MAO BAIYANG, WANG ZHIGANG, XIE RUILI, GUO WEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a clopidogrel bisulfate tablet and a preparation method thereof. Each clopidogrel bisulfate tablet comprises 25-75 mg of clopidogrel bisulfate measured in the term of clopidogre, fillers, disintegrants, solubilizers, flow aids and lubricants. In the invention, the method of adding granular microcrystalline cellulose and aerosil through airflow crushing disposal to a prescription is adopted, therefore, the process of dry granulating is simple and feasible, reproducibility is good, prepared products have high stability, and the requirement of continuous large-scale production can be satisfied.