Darifenacin hydrobromide sustained-release tablet and preparation method

The invention belongs to the field of new medicament technologies, and in particular relates to a darifenacin hydrobromide sustained-release tablet and a preparation method. The darifenacin hydrobromide sustained-release tablet adopts carbomer as a new retardant, and the dosage of the carbomer is 1-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: XING LAITIAN, JIAO PEIXIANG, QIN YURONG, LV CHUANTAO, YAN ZHIMENG
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention belongs to the field of new medicament technologies, and in particular relates to a darifenacin hydrobromide sustained-release tablet and a preparation method. The darifenacin hydrobromide sustained-release tablet adopts carbomer as a new retardant, and the dosage of the carbomer is 1-5% by weight of the preparation and can reach considerable vitro release and bioavailability compared with the dosage of the retardant in the prior art, which is more than half of the dosage of a prescription. The dosage of the retardant in the new method is greatly reduced so that the consumption of materials can be greatly reduced, the process is simpler, the controllability is better, the efficiency is improved, and the production cost is greatly reduced.