Process for simultaneously preparing asiaticoside and madecassoside from low asiaticoside content total glycosides
The invention discloses a process for simultaneously preparing asiaticoside and madecassoside from low asiaticoside content total glycosides. The process comprises the following steps: 1) heating and dissolving the low asiaticoside content total glycosides with methanol at the temperature of between...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a process for simultaneously preparing asiaticoside and madecassoside from low asiaticoside content total glycosides. The process comprises the following steps: 1) heating and dissolving the low asiaticoside content total glycosides with methanol at the temperature of between 50 and 65 DEG C, and cooling and crystallizing to prepare solid object I and crystal mother solution I; 2) re-crystallizing the solid object I twice under the condition in the step 1), drying in vacuum to prepare high purity madecassoside; 3) purifying the crystal mother solution I through a macroporous adsorption resin, concentrating and drying in vacuum to prepare high asiaticoside content total glycosides, dissolving with solvent I, adding solvent II to crystallize, and drying in vacuum to prepare high purity asiaticoside; and 4) purifying the crystal mother solution through a macroporous adsorption resin, concentrating the collected solution enriching total glycosides, and drying in vacuum to be used as an ini |
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