Medicament composition for curing type 2 diabetes and preparation method thereof

The invention provides a medicament composition for curing type 2 diabetes and a preparation method thereof. The medicament composition is the medicament composition of glipizide osmotic pump tablets and thiazolidinediones; the thiazolidinedione medicament is one of pioglitazone, rosiglitazone and medicinal salts thereof; and the glipizide is 2 to 10mg, the pioglitazone is 10 to 50mg or the osiglitazone is 1 to 10mg. The preparation method comprises the following steps of preparing the glipizide osmotic pump tablets first and then enveloping the tablet cores with the pioglitazone or rosiglitazone medicaments, wherein the outer layers of the tablets also can be enveloped by dampproof membranes; and single-layer or dual-layer naked tablets are formed by tablet compressing in the semi-permeable membranes of the glipizide osmotic pump tablets. The glipizide and pioglitazone or rosiglitazone medicaments are administrated in combination to cure moderate and serious type 2 diabetes or cure the type 2 diabetes resist