Liposome composition for conveying eye treatment medicament

The invention discloses a liposome composition for conveying a treatment medicament with a large effective loading amount to an angiogenesis position of a sick eye needing the treatment medicament. The liposome composition in which the treatment medicament is encapsulated comprises a particle formin...

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Bibliographische Detailangaben
Hauptverfasser: LIU JUNREN, ZENG YUNLONG, GUO SONGSHENG, HONG JILONG, LAI QIJUN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a liposome composition for conveying a treatment medicament with a large effective loading amount to an angiogenesis position of a sick eye needing the treatment medicament. The liposome composition in which the treatment medicament is encapsulated comprises a particle forming component consisting of a plurality of vesiculation forming liposomes and a medicament carrier component capable of forming a complex together with the treatment medicament under the interaction of static electricity and static electricity or the interaction of a hydrophobic group and a hydrophobic group. The average particle size of the liposome composition comprising the treatment medicament is about 30 to 200 nanometers. The liposomes accumulated at the angiogenesis position of the eye can be detected 24 hours after the liposome composition comprising the treatment medicament is given to a patient through intravenous injection. The invention also discloses a method for conveying the treatment medicament to the