Preparation of substituted nitrogen-containing benzoheterocycle derivatives and pharmacological application thereof

The invention discloses a compound or pharmaceutically acceptable salt thereof which has the structural general formula shown in formula (I), wherein R1 is selected from any one of the following radicals: alkyl or substituted alkyl containing 1-3 carbon atoms or phenyl; the phenyl can be substituted...

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Bibliographische Detailangaben
Hauptverfasser: MIU LIYAN, DENG JING, MA SHENG, JIANG HUALIANG, LI HONGLIN, ZHU WEILIANG, LIU HONG, ZHANG YAN, LI JIAN, FENG ENGUANG, SHEN XU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a compound or pharmaceutically acceptable salt thereof which has the structural general formula shown in formula (I), wherein R1 is selected from any one of the following radicals: alkyl or substituted alkyl containing 1-3 carbon atoms or phenyl; the phenyl can be substituted by any one or more same or different following radicals: H, halogen, C1-C6 linear chain or branched chain alkyl, hydroxyl, C1-C4 alkoxy, C1-C4 unsaturated oxyl, carboxyl, carboxyl substituted C1-C6 saturated or unsaturated alkyl, cyan, nitryl, amino, trifluoromethyl, trifluoromethoxy, sulfydryl and C1-C4 acyl; R2 is selected from H or -ZR1 substituent; R3 is selected from H, nitryl, trifluoromethyl, amino or methoxyl; X and Y are respectively selected from N or CH independently; Z is selected from N or O; and n is equal to 0 or 1.