Substituted hydroxylamine derivatives with anti-inflammatory activity and preparation method and application thereof

The invention relates to the field of pharmaceutical chemistry, in particular to substituted hydroxylamine derivatives. The invention also discloses a preparation method for the substituted hydroxylamine derivatives, a medicinal composition comprising the compounds, and the application of the compou...

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Bibliographische Detailangaben
Hauptverfasser:	WANG QIUJUAN, WU XIAOMING, LIU JUN, JIANG JINGZHANG, ZHU PEIQING, HUANG XIAOJING, JIANG SIYI, HUANG JINGER, JIANG BO, XU JINYI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to the field of pharmaceutical chemistry, in particular to substituted hydroxylamine derivatives. The invention also discloses a preparation method for the substituted hydroxylamine derivatives, a medicinal composition comprising the compounds, and the application of the compounds in treating rheumatoid arthritis and osteoarthritis, and treating other diseases and symptoms through doubly inhibiting cyclooxygenase-2(COX-2) and 5-lipoxygenase (5-LOX).