Composition for antagonizing pyretic effect of endotoxin in vaccine on livestock and application thereof

The invention discloses a composition for antagonizing pyretic effect of endotoxin in vaccine on livestock and application thereof. The composition consists of polymyxin B and glycin, wherein the concentration of the polymyxin B is 200mu g/ml; and the concentration of the glycin is 200mg/ml. A mouse is taken as a model, clinical manifestation of the mouse is observed after the polymyxin B and theglycin are jointly used for the vaccine, the fatal influence of the polymyxin B and the glycin on the mouse is observed, and the optimal mixture ratio of the PMB to the Gly for jointly antagonizing the endotoxin in the vaccine is determined, namely the composition is added to the vaccine until each milliliter of the vaccine contains 2 to 4 mu g of the polymyxin B and 20 to 40mg of the glycin; thecomposition has good endotoxin combining and neutralizing capacity, can effectively antagonize the endotoxin in the vaccine, and has the synergic antagonistic effect; in addition, the two antagonistsare simultaneously applied,