Entecavir soft capsule
The invention relates to a soft capsule with an active component inhibiting hepatitis virus, in particular to an Entecavir soft capsule with high dissolubility, low penetration rate and stable property. The Entecavir soft capsule comprises a soft capsule shell and a content composition, wherein the...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a soft capsule with an active component inhibiting hepatitis virus, in particular to an Entecavir soft capsule with high dissolubility, low penetration rate and stable property. The Entecavir soft capsule comprises a soft capsule shell and a content composition, wherein the content composition comprises the following components by 100 percent of total weight of the composition: 0.05-1.0 percent of Entecavir, 80-99.85 percent of filling solvent and 0.10-5.0 percent of povidone; and the total weight of all components in the composition is 100 percent. The invention improves the dissolubility and stability of the Entecavir and can maintain a stable composition system under various conditions without precipitation; the Entecavir active component can not be changed along with the change of time and has uniform and consistent content and high storage stability, and impurities of the Entecavir active component can not increase by long-time storage. Compared with propylene glycol, the Entecav |
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