Preparation method and products of danofloxacin mesylate liposome

The invention provides a preparation method and products of danofloxacin mesylate liposome. The preparation method comprises the following steps: (1) adopting the ammonium sulfate gradient method to prepare blank liposome; and (2) adding danofloxacin mesylate liquor in the blank liposome, using water bath for incubation, filtrating, and performing repeated freeze thawing to the filtrate by using the freeze and thawing method to obtain the danofloxacin mesylate liposome. The finished liposome prepared by the preparation method of the invention is milky semitransparent mixed suspension which appears as spherical or nearly globose small vesicles with regular shape, good dispersity and uniform grain size under an electron microscope; the entrapment rate of the liposome is above 90% and the liposome has good stability; the pharmacokinetic and pharmacodynamic properties of the liposome are better than that of conventional dosage forms and the liposome is characterized by slow release, long acting and high lung-targ