Sustained-release pill of total alkaloids from strychnos and method for preparing same

The invention discloses a sustained-release pill of total alkaloids from strychnos and a method for preparing the same. The sustained-release pill of total alkaloids from strychnos has high bioavailability, controllable release and long pain-relieving time, is taken for fewer times, is safe and reli...

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Hauptverfasser: BIAN XUYUN, JIANG MINGZHU, XU DABAO, YAN HUI, GUI ZHONGZHENG
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creator BIAN XUYUN
JIANG MINGZHU
XU DABAO
YAN HUI
GUI ZHONGZHENG
description The invention discloses a sustained-release pill of total alkaloids from strychnos and a method for preparing the same. The sustained-release pill of total alkaloids from strychnos has high bioavailability, controllable release and long pain-relieving time, is taken for fewer times, is safe and reliable and can not cause pollution when being produced. The strychnine and strychnine is used as the active component of the sustained-release pill of total alkaloids from strychnos and is mixed with hydrophilic matrix material and hydrophobic matrix material which are used as matrix to prepare the sustained-release pill of total alkaloids from strychnos. The sustained-release pill of total alkaloids from strychnos comprises the following components by weight percent: 1-8 percent of the strychnine, 80-88 percent of hydrophilic matrix material and 10-12 percent of hydrophobic matrix material, wherein the hydrophilic matrix material is the mixture of polyethylene glycol 4000 and polyethylene glycol 6000, and the hydrop
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Sustained-release pill of total alkaloids from strychnos and method for preparing same
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