Sustained-release pill of total alkaloids from strychnos and method for preparing same

The invention discloses a sustained-release pill of total alkaloids from strychnos and a method for preparing the same. The sustained-release pill of total alkaloids from strychnos has high bioavailability, controllable release and long pain-relieving time, is taken for fewer times, is safe and reli...

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Bibliographische Detailangaben
Hauptverfasser: BIAN XUYUN, JIANG MINGZHU, XU DABAO, YAN HUI, GUI ZHONGZHENG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a sustained-release pill of total alkaloids from strychnos and a method for preparing the same. The sustained-release pill of total alkaloids from strychnos has high bioavailability, controllable release and long pain-relieving time, is taken for fewer times, is safe and reliable and can not cause pollution when being produced. The strychnine and strychnine is used as the active component of the sustained-release pill of total alkaloids from strychnos and is mixed with hydrophilic matrix material and hydrophobic matrix material which are used as matrix to prepare the sustained-release pill of total alkaloids from strychnos. The sustained-release pill of total alkaloids from strychnos comprises the following components by weight percent: 1-8 percent of the strychnine, 80-88 percent of hydrophilic matrix material and 10-12 percent of hydrophobic matrix material, wherein the hydrophilic matrix material is the mixture of polyethylene glycol 4000 and polyethylene glycol 6000, and the hydrop