LXR and FXR modulators

Compounds of the invention are disclosed, such as compounds of formulae LX - LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R , R , R , R , J , J , G , G , and...

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Bibliographische Detailangaben
Hauptverfasser:	JAMMALAMADAKA VASU, BOREN BRANT CLAYTON, GU XIAO-HUI, LU SHAO-PO, MOHAN RAJU, XIE YINONG, MARTIN RICHARD, WANG TIE-LIN, SCHWEIGER EDWIN, XU WEI, BUSCH BRETT B, STEVENS WILLIAM C. JR
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of the invention are disclosed, such as compounds of formulae LX - LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R , R , R , R , J , J , G , G , and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.