Bioreactor for in vitro culture of neurotrophic factors

The invention discloses a bioreactor for in vitro culture of neurotrophic factors, which comprises an upper cover and a lower cover which are provided with concave cavities. The concave cavities of the upper cover and the lower cover are closed in opposite directions and fixed to form a box body, a culture plate through which cerebrospinal fluid can pass is arranged in the cavity of the box body,a polyether sulfone semi-permeable membrane is covered on the culture plate, the culture plate is embedded to the middle lower part of the concave cavity of the lower cover and positioned between theupper cover and the lower cover, both the upper part and the lower part of the culture plate are spaces in which the cerebrospinal fluid flows, the upper cover is provided with an input nozzle, the lower cover is provided with an output nozzle, and the upper end face of the upper cover is provided with a plurality of holes through which the air enters the box body. The bioreactor enables the cerebrospinal fluid of a nervou