Method for extracting purified cortex phellodendri total alkaloid by utilizing ion-exchange fiber

The invention relates to a method for extracting purified plant medical component-total alkaloid by utilizing ion-exchange fiber, which comprises the following steps: cleaning, drying and crushing the raw cortex phellodendri for decoction and leaching; adsorbing the leached solution by an ion-exchan...

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Bibliographische Detailangaben
Hauptverfasser: CUI CHENGMIN, ZHOU SHAOJI, LIU TINGYUE, NIE SUSHUANG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a method for extracting purified plant medical component-total alkaloid by utilizing ion-exchange fiber, which comprises the following steps: cleaning, drying and crushing the raw cortex phellodendri for decoction and leaching; adsorbing the leached solution by an ion-exchange fiber column under the condition that the consistency of total alkaloid is 0.5-6.0 g.L , the temperature is 10-80 DEG C, the flow rate is 0.5-20.0 BV.h(BV: column volume ) and the pH value is 1.0 to 6.0; eluting the adsorbed solution by eluent prepared from 2 to 10 of water, alcohol and ester or the mixture thereof and 1 of pH regulator by volume ratio, wherein the eluting temperature is 10-90 DEG. C, the flow rate is 0.2-20 BV.h, the water, alcohol and ester or the mixture thereof is 5-100 percent of 4-20 times of column volume (BV), and the acid concentration of the pH regulator is 1* 10 to 3.0 mol ; and collecting the eluate, and recovering the organic matters to obtain total alkaloid pow