Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide

Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide

The invention relates to a preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide, which is realized through the following steps: performing a reaction of benzyl chloride, N, N-dimethyl para-hydroxy benzeneacetamide and alkali in a mixture ratio of (1.0 to 3.0): 1.0: (1.0 to 6.0) by equiva...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: CAI FANPING
Format: Patent
Sprache:chi ; eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator CAI FANPING
description The invention relates to a preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide, which is realized through the following steps: performing a reaction of benzyl chloride, N, N-dimethyl para-hydroxy benzeneacetamide and alkali in a mixture ratio of (1.0 to 3.0): 1.0: (1.0 to 6.0) by equivalent weight in a reaction kettle; heating to 25-120 DEG C, preserving heat for 0.5-24 hours, and cooling to -20-50 DEG C; performing centrifugation; rinsing with 30-200 kilograms of solvent; and drying in a vacuum baking oven, so as to acquire a product as a white solid. The preparation method has the advantages that N, N-dimethyl-4-benzyloxy phenyl acetamide can be massively produced and further synthesized; the technical cost is low, and the operation is simple and convenient; and the purity of the acquired product can reach more than 98 percent, and the yield can also reach more than 90 percent.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN101597238A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN101597238A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN101597238A3</originalsourceid><addsrcrecordid>eNrjZHAIKEotSCxKLMnMz1PITS3JyE9RyE9T8NNR8NNNyQQJVObomugmpeZVVebkV1QqFGSk5lXmKCQmp5Yk5mampPIwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTiAqDCvNSSeGc_QwNDU0tzI2MLR2Ni1AAAhiIwzg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide</title><source>esp@cenet</source><creator>CAI FANPING</creator><creatorcontrib>CAI FANPING</creatorcontrib><description>The invention relates to a preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide, which is realized through the following steps: performing a reaction of benzyl chloride, N, N-dimethyl para-hydroxy benzeneacetamide and alkali in a mixture ratio of (1.0 to 3.0): 1.0: (1.0 to 6.0) by equivalent weight in a reaction kettle; heating to 25-120 DEG C, preserving heat for 0.5-24 hours, and cooling to -20-50 DEG C; performing centrifugation; rinsing with 30-200 kilograms of solvent; and drying in a vacuum baking oven, so as to acquire a product as a white solid. The preparation method has the advantages that N, N-dimethyl-4-benzyloxy phenyl acetamide can be massively produced and further synthesized; the technical cost is low, and the operation is simple and convenient; and the purity of the acquired product can reach more than 98 percent, and the yield can also reach more than 90 percent.</description><language>chi ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20091209&amp;DB=EPODOC&amp;CC=CN&amp;NR=101597238A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25546,76297</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20091209&amp;DB=EPODOC&amp;CC=CN&amp;NR=101597238A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAI FANPING</creatorcontrib><title>Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide</title><description>The invention relates to a preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide, which is realized through the following steps: performing a reaction of benzyl chloride, N, N-dimethyl para-hydroxy benzeneacetamide and alkali in a mixture ratio of (1.0 to 3.0): 1.0: (1.0 to 6.0) by equivalent weight in a reaction kettle; heating to 25-120 DEG C, preserving heat for 0.5-24 hours, and cooling to -20-50 DEG C; performing centrifugation; rinsing with 30-200 kilograms of solvent; and drying in a vacuum baking oven, so as to acquire a product as a white solid. The preparation method has the advantages that N, N-dimethyl-4-benzyloxy phenyl acetamide can be massively produced and further synthesized; the technical cost is low, and the operation is simple and convenient; and the purity of the acquired product can reach more than 98 percent, and the yield can also reach more than 90 percent.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAIKEotSCxKLMnMz1PITS3JyE9RyE9T8NNR8NNNyQQJVObomugmpeZVVebkV1QqFGSk5lXmKCQmp5Yk5mampPIwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTiAqDCvNSSeGc_QwNDU0tzI2MLR2Ni1AAAhiIwzg</recordid><startdate>20091209</startdate><enddate>20091209</enddate><creator>CAI FANPING</creator><scope>EVB</scope></search><sort><creationdate>20091209</creationdate><title>Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide</title><author>CAI FANPING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN101597238A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2009</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>CAI FANPING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CAI FANPING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide</title><date>2009-12-09</date><risdate>2009</risdate><abstract>The invention relates to a preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide, which is realized through the following steps: performing a reaction of benzyl chloride, N, N-dimethyl para-hydroxy benzeneacetamide and alkali in a mixture ratio of (1.0 to 3.0): 1.0: (1.0 to 6.0) by equivalent weight in a reaction kettle; heating to 25-120 DEG C, preserving heat for 0.5-24 hours, and cooling to -20-50 DEG C; performing centrifugation; rinsing with 30-200 kilograms of solvent; and drying in a vacuum baking oven, so as to acquire a product as a white solid. The preparation method has the advantages that N, N-dimethyl-4-benzyloxy phenyl acetamide can be massively produced and further synthesized; the technical cost is low, and the operation is simple and convenient; and the purity of the acquired product can reach more than 98 percent, and the yield can also reach more than 90 percent.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_CN101597238A
source esp@cenet
subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T11%3A04%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CAI%20FANPING&rft.date=2009-12-09&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN101597238A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true