Preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide

The invention relates to a preparation method of N, N-dimethyl-4-benzyloxy phenyl acetamide, which is realized through the following steps: performing a reaction of benzyl chloride, N, N-dimethyl para-hydroxy benzeneacetamide and alkali in a mixture ratio of (1.0 to 3.0): 1.0: (1.0 to 6.0) by equivalent weight in a reaction kettle; heating to 25-120 DEG C, preserving heat for 0.5-24 hours, and cooling to -20-50 DEG C; performing centrifugation; rinsing with 30-200 kilograms of solvent; and drying in a vacuum baking oven, so as to acquire a product as a white solid. The preparation method has the advantages that N, N-dimethyl-4-benzyloxy phenyl acetamide can be massively produced and further synthesized; the technical cost is low, and the operation is simple and convenient; and the purity of the acquired product can reach more than 98 percent, and the yield can also reach more than 90 percent.