Anti-KIR antibodies, formulations, and uses thereof

A novel IgG4 isotype anti-KIR antibody, novel formulations of this and other IgG4 anti-KIR antibodies, and methods of using such formulations are provided. Also described are compositions, formulations, dosages, and administration regimens suitable for NK cell activation and therapeutic applications...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SVENDSEN IVAN, OVERGAARD RUNE VIIG, SVENSSON ROZANA, ALIFRANGIS LENE HJORTH, WAGTMANN PETER ANDREAS NICOLAI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A novel IgG4 isotype anti-KIR antibody, novel formulations of this and other IgG4 anti-KIR antibodies, and methods of using such formulations are provided. Also described are compositions, formulations, dosages, and administration regimens suitable for NK cell activation and therapeutic applications of anti-KIR antibodies, as well as kits comprising one or more anti-KIR antibodies with instructions for use in treating cancer.