Organic-inorganic hybrid chiral sorbent and process for the preparation thereof

The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2- phenyl propionic acid, diethyl tartrate, 2,2'-dihydroxy-1,1 '-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral sep...

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Bibliographische Detailangaben
Hauptverfasser:	MAYANI VISHAL JITENDRABHAI, KURESHY RUKHSANA ILYAS, ABDI SYED HASAN RAZI, AGARWAL SANTOSH, JASRA RAKSH VIR
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2- phenyl propionic acid, diethyl tartrate, 2,2'-dihydroxy-1,1 '-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral separation (enantiomeric excess, 99 %) in case of mandelic acid under medium pressure column chromatography. These optically pure enantiomers find applications as intermediates in pharmaceutical industries.