Mucous membrane immunologic adjuvant using heat-sensitive colitoxin dual-mutant as vaccine

The invention discloses a separated heat-sensitive colitoxin mutant protein. Compared with A subunit of wild type heat-sensitive colitoxin, A subunit of the protein has the 63th position of the amino acid sequence being K, the 192nd position being G, or the 72nd position being R, and the 192nd posit...

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Bibliographische Detailangaben
Hauptverfasser:	PAN JIE, ZHAO YANMIN, TANG SIJING, RAO BAIZHONG, LIU HUILI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a separated heat-sensitive colitoxin mutant protein. Compared with A subunit of wild type heat-sensitive colitoxin, A subunit of the protein has the 63th position of the amino acid sequence being K, the 192nd position being G, or the 72nd position being R, and the 192nd position being G. The invention also discloses a coding gene of the protein, a carrier or cell containingthe gene, an adjuvant composite containing the protein, and a production method of the protein.