Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones

This invention provides a compound of formula (I) or a pharmaceutically acceptable salt, solvate or N-oxide thereof: The invention also relates to processes for the preparation of compounds of formula (I), pharmaceutical compositions containing compounds of formula (I) and to the use of compounds of...

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Hauptverfasser: DABBS STEVEN, GIORDANO ILARIA, HENNESSY ALAN JOSEPH, BROOKS GERALD, FIANDOR ROMAN JOSE MARIA, HOFFMAN JAMES B, JONES GRAHAM ELGIN, ROSSI JASON ANTHONY, BALLELL LLUIS, BARROS DAVID, PEARSON NEIL DAVID, ZHANG LIHUA LILY, DAVIES DAVID THOMAS, DAINES ROBERT A, MILES TIMOTHY JAMES, PENDRAK ISRAIL, CASTRO PICHEL JULIA, REMUINAN BLANCO MODESTO J
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:This invention provides a compound of formula (I) or a pharmaceutically acceptable salt, solvate or N-oxide thereof: The invention also relates to processes for the preparation of compounds of formula (I), pharmaceutical compositions containing compounds of formula (I) and to the use of compounds of formula (I) in the manufacture of a medicament for use in the treatment of bacterial infections including tuberculosis in mammals.