Amino acid surrogates for peptidic constructs

Ring-constrained amino acid surrogates of formula (I) where R1, R2, R3, R4, R5, R6a, R6b, R7, and y are as defined in the specification, methods for synthesizing ring-constrained amino acid surrogates of formula (I), methods of use of ring-constrained amino acid surrogates of formula I, including us...

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Bibliographische Detailangaben
Hauptverfasser: SHARMA SHUBH D, CAI HUI-ZHI, YANG WEI, BASTOS MARGARITA
Format: Patent
Sprache:eng
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Zusammenfassung:Ring-constrained amino acid surrogates of formula (I) where R1, R2, R3, R4, R5, R6a, R6b, R7, and y are as defined in the specification, methods for synthesizing ring-constrained amino acid surrogates of formula (I), methods of use of ring-constrained amino acid surrogates of formula I, including use in linear or cyclic compounds which include a plurality of amino acid residues and one or more ring-constrained amino acid surrogates of formula I and linear or cyclic compounds which include a plurality of amino acid residues and one or more ring-constrained amino acid surrogates of formula I.