Method for purification of cytidinediphosphoric choline

A method for purification of cytidinediphosphoric choline comprises the steps of contacting a cytidinediphosphoric choline solution having a pH of 0.5 to 5.0 (inclusive) and containing a nucleic acid analogue with a H-type strongly acidic cation exchange resin, and eluting cytidinediphosphoric choli...

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Hauptverfasser: MURATA HIDEKI, MOKUDAI TSUYOSHI, SHIOMI MICHIO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A method for purification of cytidinediphosphoric choline comprises the steps of contacting a cytidinediphosphoric choline solution having a pH of 0.5 to 5.0 (inclusive) and containing a nucleic acid analogue with a H-type strongly acidic cation exchange resin, and eluting cytidinediphosphoric choline adsorbed on the resin with water or an aqueous solution having an ion concentration of 0.1 mol/L or lower to thereby isolate and purify cytidinediphosphoric choline.