Method for generating amino acid by enterobacteria

A method for producing an L-amino acid is described, for example, L-phenylalanine and L-histidine, by fermentation using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified by attaching a DNA fragment able to be transcribed encoding the peptide represented in SEQ ID...

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Bibliographische Detailangaben
Hauptverfasser: DOROSHENKO VERA GEORGIEVNA, AIRIKH LARISA GOTLIBOVNA, SHAKULOV RUSTEM SAIDOVICH, KLYACHKO ELENA VITALIEVNA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A method for producing an L-amino acid is described, for example, L-phenylalanine and L-histidine, by fermentation using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified by attaching a DNA fragment able to be transcribed encoding the peptide represented in SEQ ID NO: 2, or a variant thereof, particularly a portion of the ssrA gene, to the 3′-end of gene encoding for the bacterial enzyme, which influences on the L-amino acid biosynthesis, such as chorismate mutase/prephenate dehydrogenase or phosphoglucose isomerase.