Novel dual nk2/nk3-antagonists, pharmaceutical compositions comprising them and processes for their preparations

The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation...

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Hauptverfasser: JASSERAND DANIEL, BENSON WERNER, FIRNGES MICHAEL, JAUNZEMS JANIS, BRUECKNER REINHARD, SCHOEN UWE, MCCREARY ANDREW CHRISTOPHER, REICHE DANIA, MENTZEL MATTHIAS, SANN HOLGER, ADOLFS MARTINUS, ATTALI AMOS, SMID PETER, PREUSCHOFF ULF
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation of the novel dual NK2/NK3-antagonists and to their uses.