Curcumin nano crystallization preparation and preparation method thereof

The invention relates to a curcumin nano crystal formulation and a preparation thereof. The formulation consists of curcumin and a surface active agent, can be prepared to be lyophilized powders and used for oral dosing. The nano crystal can increase the solubility of the curcumin, promote the absor...

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Bibliographische Detailangaben
Hauptverfasser: ZHAI GUANGXI, GAO YAN, LIU ANCHANG, LI HOULI, CAO FENGLIANG, LOU HONGXIANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a curcumin nano crystal formulation and a preparation thereof. The formulation consists of curcumin and a surface active agent, can be prepared to be lyophilized powders and used for oral dosing. The nano crystal can increase the solubility of the curcumin, promote the absorption thereof in gastrointestinal tract and improve bioavailability. The absorption efficiency of the curcumin nano crystal in the gastrointestinal tract is higher than that of the curcumin micelle formulation obviously, therefore the oral absorption of the curcumin and the bioavailability are improved.